Construction of the Shalun Smart Green Energy Science City in Tainan began in November 2016, coordinated by the Executive Yuan and involving 13 ministries. The National Science and Technology Council (NSTC) is responsible for the Artificial Intelligence (AI) Industrial Zone, which is located near the Tainan HSR Station and covers 5.33 hectares. The zone's Cybersecurity and Smart Technology R&D Building, completed in 2020 and focused on cybersecurity and smart technology, officially opened on April 24, 2021, providing space for research teams and fostering industry-academia-research collaboration.

The building consists of six floors above ground and two levels below, focusing on four primary developmental pillars: Cybersecurity, Smart Transportation, Smart Health, and Smart Living. Its core facilities include the Cybersecurity Training Academy, Cybersecurity Collaboration Base, Industrial Control Attack and Defense Base, Smart Transportation Simulation Platform, and TTA SOUTH (Taiwan Tech Arena South). Other spaces are dedicated to attracting R&D firms specializing in cybersecurity and smart technology, research institutes, and international corporations, creating a complete support chain from startup incubation to product verification, thereby forming an industrial ecosystem for co-creation and demonstration applications.

The building has been awarded dual Diamond-grade certifications for both Smart Building and Green Building standards. Its integrated solar photovoltaic and wind power systems have a total capacity of 687 kW, generating approximately 750,000 kWh annually. This reduces carbon emissions by 389 metric tons, equivalent to the annual carbon sequestration of Taipei’s Da’an Forest Park. Furthermore, a Regional Energy Management System (REMS) integrates the power grids of the R&D building and the autonomous driving test site to optimize energy efficiency. A rainwater harvesting system, known as a 'Water Bank,' is also implemented for irrigation and landscaping.

Regarding intelligent management, the building utilizes a 5D Visualization Platform that integrates Geographic Information Systems (GIS), Building Information Modeling (BIM), and various sensing devices, including HVAC, lighting, surveillance, EV charging piles, solar panels, and seismographs. The platform provides real-time facility status updates, assisting managers in monitoring, analyzing, and responding to anomalies, which effectively enhances operational efficiency and safety management.

To promote demonstration and exchange, a 230-ping (approx. 760 sq. m) open exhibition space is located on the first floor, featuring a mobile giant screen (7 meters high by 21 meters wide) and two sets of high-efficiency projection equipment suitable for exhibitions and large-scale events. The first floor also houses a 300-seat international conference hall and two 80-seat meeting rooms, while the second floor provides two medium-sized meeting rooms for 20–25 people to meet the needs of seminars, education, and collaboration.